Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567302 | 0.83 | RECQL (0.43) | RECQLTP53CA2CA1CPB2 | |
| SCHEMBL8781747 | 0.79 | CA2 (0.47) | TP53CA2CA1TDP1MAPK1 | |
| SCHEMBL9567278 | 0.76 | ZDHHC7 (0.43) | TP53CA2CPB2MMP9MMP13 | |
| SCHEMBL28398863 | 0.76 | RECQL (0.48) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL9621468 | 0.76 | RECQL (0.48) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL27395385 | 0.76 | RECQL (0.48) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL9618775 | 0.76 | RECQL (0.48) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL29506776 | 0.75 | RECQL (0.47) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL1483872 | 0.75 | RECQL (0.47) | RECQLTP53CA2CPB2MMP9 | |
| SCHEMBL1173438 | 0.75 | RECQL (0.47) | RECQLTP53CA2CPB2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667724-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005028516-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2005-03-31 | — | — | WO | disclosed |