Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hc Blue No. 1 SCHEMBL29683680 | 0.82 | ALDH1A1 (0.73) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| Hc Blue No. 1 SCHEMBL2467623 | 0.82 | ALDH1A1 (0.73) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL16210923 | 0.82 | ALDH1A1 (0.73) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL109266 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL29829407 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL198602 | 0.79 | ALDH1A1 (0.85) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL30808004 | 0.79 | ALDH1A1 (0.85) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL8893132 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL111343 | 0.78 | ALDH1A1 (0.83) | ALDH1A1TDP1TSHRMAPTNPSR1 | |
| SCHEMBL109353 | 0.78 | TDP1 (0.67) | ALDH1A1TDP1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660022-B1 | AGENT FOR COLOURING KERATIN FIBRES | HFC PRESTIGE INT HOLDING SWITZERLAND S A R L (CH) | 2017-04-12 | — | — | EP | disclosed |
| EP-1660022-A2 | AGENT FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005032502-A2 | AGENT FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2005-04-14 | — | — | WO | disclosed |