Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.57 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694698 | 1.00 | SRD5A2 (0.58) | SRD5A2CYP26A1CYP26B1HDAC2HCAR2 | |
| SCHEMBL5694789 | 0.91 | CYP26A1 (0.59) | SRD5A2CYP26A1CYP26B1HDAC2HCAR2 | |
| SCHEMBL5694786 | 0.91 | CYP26A1 (0.59) | SRD5A2CYP26A1CYP26B1HDAC2HCAR2 | |
| SCHEMBL5694689 | 0.84 | L3MBTL1 (0.61) | CYP26A1CYP26B1HCAR2ESR1ESR2 | |
| SCHEMBL5694692 | 0.84 | L3MBTL1 (0.61) | CYP26A1CYP26B1HCAR2ESR1ESR2 | |
| SCHEMBL5694791 | 0.84 | CYP26A1 (0.55) | SRD5A2CYP26A1CYP26B1HDAC2HCAR2 | |
| SCHEMBL5694812 | 0.84 | CYP26A1 (0.59) | CYP26A1CYP26B1HCAR2ESR1ESR2 | |
| SCHEMBL5694788 | 0.84 | CYP26A1 (0.55) | SRD5A2CYP26A1CYP26B1HDAC2HCAR2 | |
| SCHEMBL5694813 | 0.84 | CYP26A1 (0.59) | CYP26A1CYP26B1HCAR2ESR1ESR2 | |
| SCHEMBL165794 | 0.82 | HDAC2 (0.75) | SRD5A2HDAC2HCAR2HDAC3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094055-B1 | NOVEL VINYLBENZENE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6329547-B1 | USEFUL AS THERAPEUTIC AGENTS FOR GLAUCOMA | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1094055-A1 | NOVEL VINYLBENZENE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |