SCHEMBL5694897

SCHEMBL5694897

O=S(=O)(O)CCCN1C(=Cc2sc3ccc4ccccc4c3[n+]2CCCS(=O)(=O)O)Sc2ccc(Cl)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.41
▸ TDP1 Q9NUW8 6/20 0.41
▸ KDM4E B2RXH2 5/20 0.41
▸ MAPK1 P28482 5/20 0.41
▸ RAD52 P43351 3/20 0.41
▸ TP53 P04637 3/20 0.41
▸ CYP3A4 P08684 3/20 0.41
▸ USP2 O75604 2/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CYP2D6 P10635 4/20 0.36
▸ KIF11 P52732 1/20 0.36
▸ HPGD P15428 2/20 0.35
▸ POLB P06746 4/20 0.35
▸ CYP2C19 P33261 4/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ LMNA P02545 6/20 0.34
▸ MEN1 O00255 5/20 0.34
▸ KMT2A Q03164 5/20 0.34
▸ APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694896 1.00 MAPT (0.41) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13632401 0.92 MAPT (0.36) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13864665 0.91 POLB (0.36) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL14574115 0.90 MAPT (0.34) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13648514 0.89 MAPT (0.42) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13864724 0.89 MAPT (0.42) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13864637 0.89 MAPT (0.35) MAPTTDP1KDM4EMAPK1RAD52
SCHEMBL13864649 0.88 POLB (0.35) MAPTTDP1KDM4EMAPK1CYP3A4
SCHEMBL13864617 0.88 POLB (0.33) MAPTTDP1KDM4EMAPK1HPGD
SCHEMBL13864668 0.87 MEN1 (0.37) MAPTTDP1KDM4EMAPK1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 — — US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 — — US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 — — US disclosed
EP-1424593-B1 Thermally developable materials containing backside conductive layer EASTMAN KODAK CO (US) 2006-04-26 — — EP disclosed
WO-2005050311-A1 STABILIZED HIGH-SPEED EMULSIONS AND PHOTOTHERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 2005-06-02 — — WO disclosed
US-20050106514-A1 Stabilized high-speed thermally developable emulsions and photothermographic materials EASTMAN KODAK COMPANY 2005-05-19 — — US disclosed
US-6849392-B2 Thermally developable emulsions and materials containing triazine-thione compounds EASTMAN KODAK COMPANY (US) 2005-02-01 — — US disclosed
WO-2005001565-A1 PHOTOTHERMOGRAPHIC MATERIALS WITH IMPROVED IMAGE TONE EASTMAN KODAK COMPANY (US) 2005-01-06 — — WO disclosed
EP-1439413-A1 Thermally developable materials having barrier layer comprising inorganic filler particles EASTMAN KODAK COMPANY (US) 2004-07-21 — — EP disclosed
US-20040137382-A1 Thermally developable emulsions and materials containing triazine-thione compounds CARESTREAM HEALTH, INC. 2004-07-15 — — US disclosed
US-6746831-B1 BARRIER LAYER CAPABLE OF RETARDING DIFFUSION OF OR REACTING WITH LONG CHAIN ALIPHATIC CARBOXYLIC ACIDS FORMED FROM THEIR SILVER SALTS WHICH ARE NON-PHOTOSENSITIVE SOURCE OF REDUCIBLE SILVER IONS EASTMAN KODAK COMPANY 2004-06-08 — — US disclosed
EP-1424593-A2 Thermally developable materials containing backside conductive layer EASTMAN KODAK COMPANY (US) 2004-06-02 — — EP disclosed
US-6737227-B1 AND ASCORBIC ACID OR REDUCTONE REDUCING AGENTS; THERMOGRAPHIC AND PHOTOTHERMOGRAPHIC; INCREASED IMAGE DENSITY AND SHORTENED DEVELOPMENT TIME, DEVELOPMENT AT LOWER TEMPERATURES EASTMAN KODAK COMPANY 2004-05-18 — — US disclosed
EP-1416324-A1 Thermally developable emulsions and imaging materials containing phthalazine compounds EASTMAN KODAK COMPANY (US) 2004-05-06 — — EP disclosed
US-6703191-B1 COMPRISING A BINDER AND IN REACTIVE ASSOCIATION, A PHOTOSENSITIVE SILVER HALIDE, A NON-PHOTOSENSITIVE SOURCE OF REDUCIBLE SILVER IONS, A REDUCING COMPOSITION FOR SAID NON-PHOTOSENSITIVE SOURCE REDUCIBLE SILVER IONS EASTMAN KODAK COMPANY 2004-03-09 — — US disclosed
US-6689546-B1 HAVING METAL ANTIMONATE CONDUCTIVE PARTICLES BURIED BENEATH PROTECTIVE OVERCOAT; STATIC FREE DEVELOPED FILMS EVEN AFTER PROLONGED STORAGE EASTMAN KODAK COMPANY 2004-02-10 — — US disclosed
US-6667148-B1 Imaging layer containing a non-photosensitive source of reducible silver ions. EASTMAN KODAK COMPANY 2003-12-23 — — US disclosed
US-6605418-B1 Thermographic and photothermographic emulsions include certain quaternary phthalazines; storage stable toner EASTMAN KODAK COMPANY 2003-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004923-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 MAPT 2437/4885TDP1 2835/4885KDM4E 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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