SCHEMBL5695347

SCHEMBL5695347

CCCCCCCC[SiH2]C1CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.40
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.31
NAAA Q02083 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20263534 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL596015 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL10935561 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL796160 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL9842827 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL8432004 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL9847970 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL28507302 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL5335212 1.00 EPHX1 (0.40) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL5969375 0.98 EPHX1 (0.37) EPHX1ALDH1A1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2025-12-02 US claimed
US-20230271848-A1 Metal Oxide Nanoparticle With Alkylsiloxane Ligands Bonded Thereto CUBICPV INC. 2023-08-31 US claimed
WO-2023123579-A1 STYRENE-ACRYLIC-SILOXANE COMPOSITE CORE-SHELL EMULSION, PREPARATION METHOD THEREFOR, AND USE THEREOF 青岛理工大学 2023-07-06 WO claimed
US-11685666-B2 Metal oxide nanoparticles with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2023-06-27 US claimed
WO-2023103997-A1 FLUORINE-FREE, WATERPROOF AND MOISTURE-PROOF SUPERHYDROPHOBIC ACTIVATED CARBON, AND PREPARATION METHOD THEREFOR AND USE THEREOF 东南大学 2023-06-15 WO claimed
EP-4066292-A1 METAL OXIDE NANOPARTICLE ELECTRON TRANSPORT LAYERS IN PEROVSKITE SEMICONDUCTOR DEVICES CubicPV Inc. (US) 2022-10-05 EP claimed
WO-2021108754-A1 METAL OXIDE NANOPARTICLE ELECTRON TRANSPORT LAYERS IN PEROVSKITE SEMICONDUCTOR DEVICES HUNT PEROVSKITE TECHNOLOGIES, L.L.C. (US) 2021-06-03 WO claimed
US-20210155497-A1 METAL OXIDE NANOPARTICLE ELECTRON TRANSPORT LAYERS IN PEROVSKITE SEMICONDUCTOR DEVICES CUBICPV INC. 2021-05-27 US claimed
CN-111728885-A Skin care composition with waterproof and sweat-proof effects, preparation method and application thereof, and cosmetic 广州美兮生物科技有限公司 2020-10-02 CN claimed
CN-111635677-A Waterproof coating 郑州艾比利特节能科技有限公司 2020-09-08 CN claimed
EP-0309489-A4 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL. VARIAN ASSOCIATES (US) 1989-09-11 EP claimed
EP-0309489-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1989-04-05 EP claimed
WO-1988007886-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1988-10-20 WO claimed
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2025-12-02 US disclosed
CN-119700586-A Oil phase inclusion, oil phase inclusion preparation method and water-based skin care composition 深圳市护家科技有限公司 2025-03-28 CN disclosed
US-20230271848-A1 Metal Oxide Nanoparticle With Alkylsiloxane Ligands Bonded Thereto CUBICPV INC. 2023-08-31 US disclosed
WO-2000032533-A1 POROUS INORGANIC MATERIAL ECC INTERNATIONAL LIMITED (GB) 2000-06-08 WO disclosed
EP-0309489-A4 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL. VARIAN ASSOCIATES (US) 1989-09-11 EP disclosed
EP-0309489-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1989-04-05 EP disclosed
WO-1988007886-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1988-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto MACO1, CD4, ITGAV EPHX1 4443/4885ALDH1A1 3555/4885TDP1 4776/4885
US-20230271848-A1 Metal Oxide Nanoparticle With Alkylsiloxane Ligands Bonded Thereto MACO1, CD4, ITGAV EPHX1 4443/4885ALDH1A1 3555/4885TDP1 4776/4885
US-11685666-B2 Metal oxide nanoparticles with alkylsiloxane ligands bonded thereto MACO1, IPO4, ITGB5 EPHX1 4360/4885ALDH1A1 4279/4885TDP1 4715/4885
US-20210155497-A1 METAL OXIDE NANOPARTICLE ELECTRON TRANSPORT LAYERS IN PEROVSKITE SEMICONDUCTOR DEVICES ITGB5, ITGA5, MACO1 EPHX1 3622/4885ALDH1A1 2691/4885TDP1 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.