Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | MITF | O75030 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CD40 | P25942 | 1/20 | 0.61 |
| ▸ | CD40LG | P29965 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27362324 | 0.98 | MEN1 (0.97) | MEN1KMT2ANPC1RAB9AMITF | |
| Iodide SCHEMBL30758586 | 0.98 | MEN1 (0.97) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL3160310 | 0.93 | MEN1 (0.87) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL23898948 | 0.91 | KMT2A (0.83) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL9134339 | 0.91 | KMT2A (0.83) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL8572381 | 0.91 | KMT2A (0.83) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL12218318 | 0.91 | MEN1 (0.82) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL7881346 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL7696438 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL6855014 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | claimed |
| US-20200231550-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-07-23 | — | — | US | claimed |
| WO-2018151681-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2018-08-23 | — | — | WO | claimed |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-10-10 | — | — | US | claimed |
| US-20260125340-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | BASF SE (DE) | 2026-05-07 | — | — | US | disclosed |
| EP-4598900-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | BASF SE (DE) | 2025-08-13 | — | — | EP | disclosed |
| CN-119998260-A | Process for preparing amides from esters | 巴斯夫欧洲公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-118048636-B | Electrocatalytic synthesis method for N-aryl amide | 平顶山学院 | 2024-09-13 | — | — | CN | disclosed |
| CN-118048636-A | Electrocatalytic synthesis method for N-aryl amide | 平顶山学院 | 2024-05-17 | — | — | CN | disclosed |
| WO-2024074641-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | BASF SE (DE) | 2024-04-11 | — | — | WO | disclosed |
| US-11078165-B2 | Compounds for treating tuberculosis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-08-03 | — | — | US | disclosed |
| US-11078165-B2 | Compounds for treating tuberculosis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-08-03 | — | — | US | disclosed |
| CN-1098402-A | Preparation method and product thereof to the nitryl aromatic acid amides | MONSANTO CO (US) | 1995-02-08 | — | — | CN | disclosed |
| US-5380946-A | From nitrobenzene and a nitrile | MONSANTO COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5331099-A | Process for preparing p-nitroaromatic amides and products thereof | MONSANTO COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1994008953-A1 | PROCESS FOR PREPARING ISOCYANATE AND CARBAMATE ESTER PRODUCTS | MONSANTO COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1993024447-A1 | PROCESS FOR PREPARING P-NITROAROMATIC AMIDES AND PRODUCTS THEREOF | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5233010-A | Reacting carbon dioxide and an aromatic diamine in an aprotic solvent and a base to produce a carbamate salt; dehydration; reacting an amide with nitrobenzene and reducing to obtain the amine | MONSANTO COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-4499167-A | Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0065395-A2 | Improved chymopapain and method for its production and use | BOOTS-FLINT, INC. (a Delaware corp.) (US) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125340-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | CBR1, CBR3, SCO2 | MEN1 2007/4885KMT2A 1928/4885NPC1 549/4885 |
| US-11078165-B2 | Compounds for treating tuberculosis | ATP5ME, ATP5MG, ATP5F1D | MEN1 4589/4885KMT2A 2920/4885NPC1 1580/4885 |
| US-20200231550-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | ATP5ME, ATP5MG, ATP5F1D | MEN1 4589/4885KMT2A 2920/4885NPC1 1580/4885 |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | NAAA, AADAC, NISCH | MEN1 4420/4885KMT2A 261/4885NPC1 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.