Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157297 | 0.92 | TMEM97 (0.39) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL11961354 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL27695059 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL11961361 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL1487127 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL11961360 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL11961357 | 0.85 | TMEM97 (0.38) | HTTTMEM97SIGMAR1MAPTSLC6A2 | |
| SCHEMBL7991267 | 0.80 | TMEM97 (0.36) | HTTTMEM97SIGMAR1MAPTSLC1A3 | |
| SCHEMBL19619434 | 0.78 | BCHE (0.33) | HTTTMEM97SIGMAR1MAPTCYP1A2 | |
| SCHEMBL8743570 | 0.78 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669355-A1 | Aminotetrahydropteridines and processes for manufacture thereof | Vasopharm Biotech GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |