Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157297 | 0.84 | TMEM97 (0.39) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL5696158 | 0.80 | HTT (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL27695059 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL11961361 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL11961357 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL1487127 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL11961354 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL11961360 | 0.76 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL19320700 | 0.74 | TMEM97 (0.42) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 | |
| SCHEMBL14884574 | 0.74 | TMEM97 (0.38) | TMEM97SIGMAR1MAPTSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194589-B1 | USEFUL AS AN HIV(HUMAN IMMUNODEFICIENCY VIRUS) PROTEASE INHIBITOR; AS X-RAY CONTRAST MEDIUM | JAPAN TOBACCO INC. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6018066-A | Production of amide derivatives and intermediate compounds therefor | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |