Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13030444 | 0.89 | NPC1 (0.77) | NPC1MEN1KMT2ANOTUMGFER | |
| SCHEMBL19756253 | 0.84 | NPC1 (0.66) | NPC1MEN1KMT2ANOTUMGFER | |
| SCHEMBL14747697 | 0.84 | NPC1 (0.70) | NPC1MEN1KMT2ANOTUMGFER | |
| SCHEMBL15248942 | 0.84 | NPC1 (0.47) | NPC1CYP1A2 | |
| SCHEMBL19756251 | 0.84 | NPC1 (0.70) | NPC1MEN1KMT2ANOTUMGFER | |
| SCHEMBL13886328 | 0.82 | NPC1 (0.68) | NPC1MEN1KMT2ANOTUMGFER | |
| SCHEMBL16132647 | 0.81 | CNR1 (0.50) | NPC1MEN1KMT2AGAAMAPT | |
| SCHEMBL8378539 | 0.81 | NPC1 (0.66) | NPC1MEN1KMT2ANOTUMMAPT | |
| SCHEMBL6681453 | 0.81 | NPC1 (0.66) | NPC1MEN1KMT2ANOTUMMAPT | |
| SCHEMBL6516972 | 0.81 | NPC1 (0.66) | NPC1MEN1KMT2ANOTUMGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273213-B2 | Special UV absorbers for curable UV-protective coatings | COVESTRO DEUTSCHLAND AG (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20130236743-A1 | SPECIAL UV ABSORBERS FOR CURABLE UV-PROTECTIVE COATINGS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-12 | — | — | US | disclosed |
| EP-1472088-B1 | ULTRAVIOLET PROTECTED MULTI-LAYER STRUCTURES OF COPOLYESTER/POLYCARBONATE BLENDS | EASTMAN CHEM CO (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1472088-A2 | ULTRAVIOLET PROTECTED MULTI-LAYER STRUCTURES OF COPOLYESTER/POLYCARBONATE BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6641920-B2 | Terephthalic acid, naphthalenedicarboxylic acid, 1,4-cyclohexanedicarboxylic acid, and 1,4-cyclohexanedimethanol comonomers; skylights, signs, glazing, laminates, packaging food, clothing, and drugs | EASTMAN CHEMICAL COMPANY | 2003-11-04 | — | — | US | disclosed |
| US-20030165685-A1 | ULTRAVIOLET PROTECTED MULTI-LAYER STRUCTURES OF COPOLYESTER/POLYCARBONATE BLENDS | EASTMAN CHEMICAL COMPANY | 2003-09-04 | — | — | US | disclosed |
| WO-2003066330-A2 | ULTRAVIOLET PROTECTED MULTI-LAYER STRUCTURES OF COPOLYESTER/POLYCARBONATE BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2003-08-14 | — | — | WO | disclosed |