Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227007 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL27773761 | 0.83 | FOLH1 (0.47) | ALDH1A1LMNAFOLH1SMN1; SMN2ADRB2 | |
| SCHEMBL27625514 | 0.82 | FOLH1 (0.46) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL3306402 | 0.82 | FOLH1 (0.66) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL5609826 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL2125820 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL30628269 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL19291183 | 0.82 | PTPN1 (0.50) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL14397902 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E | |
| SCHEMBL9331010 | 0.80 | HMGB1 (0.53) | ALDH1A1LMNAFOLH1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673375-A2 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG-Sipsy (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005035540-A2 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG-SIPSY (FR) | 2005-04-21 | — | — | WO | disclosed |