Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703568 | 0.76 | HCAR2 (1.00) | HCAR2HCAR3 | |
| SCHEMBL15931876 | 0.74 | RAB9A (0.49) | MEN1POLBMAPTKMT2ATDP1 | |
| SCHEMBL15964773 | 0.71 | HCAR2 (0.77) | HCAR2HCAR3 | |
| SCHEMBL570055 | 0.71 | MAPT (1.00) | HCAR2MEN1POLBMAPTKMT2A | |
| SCHEMBL15964774 | 0.71 | HCAR2 (0.66) | HCAR2HCAR3 | |
| SCHEMBL5599320 | 0.70 | HCAR2 (1.00) | HCAR2HCAR3 | |
| SCHEMBL15956805 | 0.70 | HCAR2 (0.74) | HCAR2HCAR3 | |
| SCHEMBL15964772 | 0.70 | HCAR2 (0.74) | HCAR2HCAR3 | |
| SCHEMBL5079518 | 0.70 | HCAR2 (1.00) | HCAR2HCAR3 | |
| SCHEMBL5083084 | 0.70 | HCAR2 (1.00) | HCAR2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |