⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6177026 | 0.97 | — | — | |
| SCHEMBL27792508 | 0.89 | FFAR3 (0.30) | — | |
| SCHEMBL4173859 | 0.87 | ALOX15 (0.37) | — | |
| SCHEMBL3247565 | 0.82 | — | — | |
| Toluene SCHEMBL11338240 | 0.80 | TSHR (0.44) | — | |
| SCHEMBL30779731 | 0.77 | GAA (0.35) | — | |
| SCHEMBL4438789 | 0.77 | — | — | |
| SCHEMBL1512269 | 0.77 | — | — | |
| SCHEMBL1163352 | 0.75 | — | — | |
| SCHEMBL10669462 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626115-B2 | Fused pyrimidinone and triazinone derivatives containing bridged nitrogen, their process of preparation and their therapeutic uses as antifungal and/or antiparasitic agents | UNIVERSITE DE NANTES (FR) | 2020-04-21 | — | — | US | claimed |
| EP-2813515-B1 | TRANSDERMALLY DELIVERED HYALURONIC ACID-PROTEIN CONJUGATE | PHI BIOMED CO LTD (KR) | 2019-07-10 | — | — | EP | claimed |
| US-20190002467-A1 | NOVEL FUSED PYRIMIDINONE AND TRIAZINONE DERIVATIVES CONTAINING BRIDGED NITROGEN, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | UNIVERSITE DE NANTES (FR) | 2019-01-03 | — | — | US | claimed |
| US-20180221366-A1 | METHODS AND COMPOSITIONS USEFUL FOR TREATING DISEASES INVOLVING BCL-2 FAMILY PROTEINS WITH QUINOLINE DERIVATIVES | EUTROPICS PHARMACEUTICALS, INC. | 2018-08-09 | — | — | US | claimed |
| US-20180200262-A1 | TARGETED NOTCH PATHWAY INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2018-07-19 | — | — | US | claimed |
| CN-108290962-A | NCC films and product based on NCC films | 美罗迪亚有限公司 | 2018-07-17 | — | — | CN | claimed |
| EP-3328862-A1 | NOVEL FUSED PYRIMIDINONE AND TRIAZINONE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS. | Universite de Nantes (FR) | 2018-06-06 | — | — | EP | claimed |
| EP-3307721-A1 | TARGETED NOTCH PATHWAY INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2018-04-18 | — | — | EP | claimed |
| CN-107438599-A | TARGETED NOTCH PATHWAY INHIBITORS | 豪夫迈·罗氏有限公司 | 2017-12-05 | — | — | CN | claimed |
| WO-2017020944-A1 | NOVEL FUSED PYRIMIDINONE AND TRIAZINONE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | UNIVERSITE DE NANTES (FR) | 2017-02-09 | — | — | WO | claimed |
| US-20050255047-A1 | Smoke composition | L. C. B. (FR) | 2005-11-17 | — | — | US | claimed |
| EP-0647884-B1 | Photoresist strippers containing reducing agents to reduce metal corrosion | MALLINCKRODT BAKER INC (US) | 1998-04-08 | — | — | EP | claimed |
| EP-0202095-B1 | PROCESS FOR PREPARING 6-AMINO-3-HYDRAZINOPYRIDAZINE DERIVATIVES | I.S.F. Socièta per Azioni (IT) | 1991-04-03 | — | — | EP | claimed |
| EP-0123066-B1 | REACTION OF CARBONYLHYDRAZINES AND ORGANIC PEROXIDES TO FOAM UNSATURATED POLYESTER RESINS | PENNWALT CORPORATION (US) | 1988-10-12 | — | — | EP | claimed |
| US-4692269-A | BLOWING AGENTS; CLOSED-CELL FOAMS | PENNWALT CORPORATION (US) | 1987-09-08 | — | — | US | claimed |
| EP-0220751-A2 | Foamable and cross-linkable unsaturated polyester composition | PENNWALT CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| EP-0220364-A2 | Reaction of certain hydrazide compounds with free radical initiators to produce crosslinked polymer foams | PENNWALT CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| EP-0219595-A2 | A gas-realising composition for tailoring gas evolution of system | PENNWALT CORPORATION (US) | 1987-04-29 | — | — | EP | claimed |
| US-4636528-A | Foaming of unsaturated polyester resin at elevated temperatures | PENNWALT CORPORATION (US) | 1987-01-13 | — | — | US | claimed |
| US-4607060-A | FREE RADICAL CATALYSIS | PENNWALT CORPORATION (US) | 1986-08-19 | — | — | US | claimed |