Sugi Predict

Sugi Predict / Compounds / SCHEMBL5697158

SCHEMBL5697158

SCHEMBL5697158

Cc1ccccc1Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.60
▸ ALDH1A1 P00352 6/20 0.59
▸ HSD17B10 Q99714 4/20 0.59
▸ TDP1 Q9NUW8 4/20 0.59
▸ ALOX15 P16050 4/20 0.59
▸ ALOX12 P18054 3/20 0.59
▸ L3MBTL1 Q9Y468 3/20 0.59
▸ TSHR P16473 3/20 0.59
▸ PTGS1 P23219 1/20 0.59
▸ SLC6A2 P23975 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ PTGS2 P35354 1/20 0.59
▸ HTR2B P41595 1/20 0.59
▸ MAPT P10636 8/20 0.52
▸ GAA P10253 4/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ RECQL P46063 2/20 0.52
▸ GLA P06280 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940926 1.00 HPGD (0.60) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL304152 0.95 MAPT (0.56) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL29653984 0.93 MAPT (0.54) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL108882 0.93 MAPT (0.54) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL12320135 0.91 MAPT (0.52) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL28235661 0.89 HPGD (0.64) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL17858148 0.87 PTGER4 (0.49) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL512863 0.86 MAPT (0.48) HPGDALDH1A1HSD17B10TDP1ALOX15
SCHEMBL3686455 0.86 GAA (0.64) HPGDTDP1L3MBTL1MAPTGAA
SCHEMBL23369883 0.85 MEN1 (0.52) HPGDALDH1A1HSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022105742-A1 ANTIDEGRADANT COMPOSITION, ANTIDEGRADANT MASTER BATCH AND RUBBER COMPOSITION SENNICS CO., LTD. (CN) 2022-05-27 — — WO claimed
US-10793510-B2 Method for preparing aryl substituted p-phenylenediamine substance SENNICS CO., LTD. (CN) 2020-10-06 — — US claimed
EP-1276804-B1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEM CO INC (US) 2006-06-14 — — EP claimed
US-6706216-B1 REACTION PRODUCT OF CATALYTIC REDUCTIVE ALKYLATION OF P-PHENYLENEDIAMINE OR DERIVATIVE WITH ACETONE AND SECOND CARBONYL COMPOUND UNIROYAL CHEMICAL COMPANY, INC. 2004-03-16 — — US claimed
US-6706217-B2 OBTAINED FROM THE REACTION OF A PARAPHENYLENEDIAMINE COMPOUND WITH ACETONE AND AT LEAST ONE OF KETONES AND ALDEHYDES, USING A REDUCTIVE ALKYLATION CATALYST UNIROYAL CHEMICAL COMPANY, INC. 2004-03-16 — — US claimed
EP-1276804-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME Uniroyal Chemical Company, Inc. (US) 2003-01-22 — — EP claimed
US-20020061946-A1 Liquid antiozonants and rubber compositions containing same ADDIVANT USA, LLC 2002-05-23 — — US claimed
WO-2001081459-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-11-01 — — WO claimed
EP-0654489-B1 High molecular weight amine containing antiozonants GOODYEAR TIRE & RUBBER (US) 1998-08-26 — — EP claimed
US-3975297-A Process of preparing free-flowing antiozonant blends THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 — — US claimed
JP-57159828-A — — None — — JP disclosed
CN-114105779-B Preparation method of asymmetric diaryl substituted p-phenylenediamine compound 圣奥化学科技有限公司 2025-04-08 — — CN disclosed
CN-115181025-B N-phenyl-N' - (p-alkylphenyl) p-phenylenediamine as well as preparation method and application thereof 山东阳谷华泰化工股份有限公司 2024-08-16 — — CN disclosed
US-12037303-B2 Method for preparing diaryl p-phenylenediamine compounds SENNICS CO., LTD. (CN) 2024-07-16 — — US disclosed
US-12037303-B2 Method for preparing diaryl p-phenylenediamine compounds SENNICS CO., LTD. (CN) 2024-07-16 — — US disclosed
JP-S57159828-A ANTIDETERIORANT FOR RUBBER SEIKOU KAGAKU KK 1982-10-02 — — JP disclosed
US-4301296-A FOR BUTADIENE-STYRENE COPOLYMER AND ACRYLONITRILE-BUTADIENE COPOLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 — — US disclosed
US-4241217-A 3,6,9-TRIOXAUNDECANE-1,11-BIS(3-DODECYLTHIOPROPIONATE) AS A LONG LASTING STABILIZER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-12-23 — — US disclosed
US-4125515-A FOR ACRYLONITRILE-BUTADIENE OR STYRENE-BUTADIENE RUBBER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-11-14 — — US disclosed
US-3975297-A Process of preparing free-flowing antiozonant blends THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037303-B2 Method for preparing diaryl p-phenylenediamine compounds C9, C1S, CCND2 HPGD 274/4885ALDH1A1 546/4885HSD17B10 512/4885
US-10793510-B2 Method for preparing aryl substituted p-phenylenediamine substance PNMT, MAOB, PAH HPGD 470/4885ALDH1A1 386/4885HSD17B10 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.