Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431399 | 0.85 | TYR (0.46) | TYRERN1LMNAHPGDBLM | |
| SCHEMBL16096543 | 0.82 | TYR (0.52) | TYRERN1ALBTLR2TLR1 | |
| SCHEMBL10910659 | 0.82 | TYR (0.41) | TYRLMNABLMTSHRALB | |
| SCHEMBL311765 | 0.81 | TYR (0.46) | TYRERN1LMNAHPGDBLM | |
| SCHEMBL311545 | 0.79 | TYR (0.44) | TYRERN1ALBTLR2TLR1 | |
| SCHEMBL10625737 | 0.78 | TYR (0.39) | TYRLMNABLMSLC6A2HTR2B | |
| SCHEMBL10611980 | 0.77 | GABRA1 (0.56) | LMNAHPGDBLMCA1CA2 | |
| SCHEMBL26229530 | 0.75 | TYR (0.41) | TYRERN1LMNAHPGDBLM | |
| SCHEMBL310825 | 0.74 | GABRA1 (0.61) | TYRERN1LMNAHPGDBLM | |
| SCHEMBL28154797 | 0.74 | TYR (0.48) | TYRERN1LMNABLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-B1 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |