SCHEMBL5697320

SCHEMBL5697320

CCC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Hf+]1OC1C.C[N-]C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6896146 0.79 BRD4 (0.31) BRD4CREBBP
SCHEMBL6897296 0.78 BRD4 (0.30) BRD4CREBBP
SCHEMBL5697330 0.78 BRD4 (0.30) BRD4CREBBP
SCHEMBL6887001 0.78 BRD4 (0.30) BRD4CREBBP
SCHEMBL6890535 0.78 BRD4 (0.35) BRD4CREBBP
SCHEMBL7198398 0.78 BRD4 (0.35) BRD4CREBBP
SCHEMBL7783132 0.78 BRD4 (0.35) BRD4CREBBP
SCHEMBL6519709 0.76
SCHEMBL7196862 0.76 SMN1; SMN2 (0.34) BRD4CREBBP
SCHEMBL7035276 0.75 BRD4 (0.33) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1334107-B1 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2006-07-26 EP disclosed
EP-1334107-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS Basell Polyolefine GmbH (DE) 2003-08-13 EP disclosed
WO-2002032908-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2002-04-25 WO disclosed