Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5697791

CC(O)C(=O)C(C)(O)C(=O)O.N

nearest known ligand 0.41

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
TET2 Q6N021 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27462516 0.98 TP53 (0.39) TP53ALDH1A1TSHRTET2
SCHEMBL30977948 0.97 TP53 (0.43) TP53ALDH1A1TSHRTET2
SCHEMBL29867947 0.97 TP53 (0.43) TP53ALDH1A1TSHRTET2
SCHEMBL4410669 0.97 TP53 (0.43) TP53ALDH1A1TSHRTET2
SCHEMBL27931388 0.95 TP53 (0.41) TP53ALDH1A1TSHRTET2
SCHEMBL28052627 0.95 TP53 (0.41) TP53ALDH1A1TSHRTET2
Water SCHEMBL2573978 0.93 TP53 (0.39) TP53ALDH1A1TSHRTET2
SCHEMBL3183247 0.86 TP53 (0.38) TP53ALDH1A1TSHRTET2
SCHEMBL7879927 0.84 TP53 (0.36) TP53ALDH1A1TSHR
SCHEMBL3985262 0.75 ALDH1A1 (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173402-B1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF TATE & LYLE INGREDIENTS (US) 2006-06-21 EP disclosed
EP-1173402-A4 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF STALEY MFG CO A E (US) 2002-08-14 EP disclosed
EP-1173402-A1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF A.E. STALEY MANUFACTURING COMPANY (US) 2002-01-23 EP disclosed
US-6291708-B1 COMBINING AQUEOUS DILUENT, AMMONIUM SALT OF ORGANIC ACID, AND ALCOHOL; HEATING UNDER PRESSURE TO DECOMPOSE THE AMMONIUM SALT OF THE ORGANIC ACID INTO AMMONIA AND FREE ORGANIC ACID WHILE REMOVING AMMONIA; RECOVERING ACID A.E. STALEY MANUFACTURING CO. 2001-09-18 US disclosed
WO-2000064850-A1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF A. E. STALEY MANUFACTURING CO. (US) 2000-11-02 WO disclosed