Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 12/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697863 | 0.87 | KCNA5 (0.69) | KCNA5FAAHL3MBTL1HPGDHTT | |
| SCHEMBL5697853 | 0.85 | KCNA5 (0.60) | KCNA5FAAHHTT | |
| SCHEMBL5697828 | 0.84 | KCNA5 (0.69) | KCNA5FAAHPOLBCYP2C19L3MBTL1 | |
| SCHEMBL5697847 | 0.83 | TAS1R3 (0.52) | KCNA5SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5697870 | 0.82 | KCNA5 (0.74) | KCNA5FAAHPOLBNPC1RAB9A | |
| SCHEMBL5697831 | 0.82 | KCNA5 (0.52) | KCNA5FAAHPOLBCYP2C19SMN1; SMN2 | |
| SCHEMBL5697846 | 0.81 | KCNA5 (0.56) | KCNA5FAAHPOLB | |
| SCHEMBL5697892 | 0.81 | KCNA5 (0.69) | KCNA5SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL2210185 | 0.81 | KCNA5 (0.76) | KCNA5POLBCYP2C19KMT2A | |
| SCHEMBL5697836 | 0.80 | KCNA5 (0.69) | KCNA5SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222163-B1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-07-12 | — | — | EP | disclosed |
| EP-1222163-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025189-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |