Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | LCLAT1 | Q6UWP7 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569244 | 0.86 | MAPT (0.43) | MAPTMEN1KMT2AKLK7LCLAT1 | |
| SCHEMBL10182473 | 0.79 | MEN1 (0.45) | MAPTMEN1KMT2AKLK7LCLAT1 | |
| SCHEMBL569407 | 0.79 | LCLAT1 (0.45) | MAPTLCLAT1TP53PTPN7 | |
| SCHEMBL570415 | 0.77 | PTPN7 (0.39) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL569329 | 0.74 | MAPK8 (0.42) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL570487 | 0.73 | NPC1 (0.45) | MAPTMEN1KMT2ALCLAT1KDM4E | |
| SCHEMBL569240 | 0.73 | MCHR1 (0.45) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL12473477 | 0.72 | MEN1 (0.37) | MAPTMEN1KMT2AKLK7LCLAT1 | |
| SCHEMBL569399 | 0.71 | TTK (0.39) | MAPTMEN1KMT2A | |
| SCHEMBL569267 | 0.70 | MAPT (0.42) | MAPTMEN1KMT2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |