Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCLAT1 | Q6UWP7 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569244 | 0.92 | MAPT (0.43) | LCLAT1MAPTLMNATP53PTPN7 | |
| SCHEMBL570415 | 0.88 | PTPN7 (0.39) | MAPTLMNATP53PTPN7 | |
| SCHEMBL569329 | 0.83 | MAPK8 (0.42) | MAPTLMNATP53 | |
| SCHEMBL570487 | 0.82 | NPC1 (0.45) | LCLAT1MAPTLMNA | |
| SCHEMBL569794 | 0.79 | MAPT (0.42) | LCLAT1MAPTTP53PTPN7 | |
| SCHEMBL569240 | 0.78 | MCHR1 (0.45) | MAPTTP53 | |
| SCHEMBL10183288 | 0.78 | LCLAT1 (0.45) | LCLAT1MAPTTP53HCRTR1PTPN7 | |
| SCHEMBL569408 | 0.78 | MAPT (0.42) | LCLAT1MAPTLMNATP53HCRTR1 | |
| SCHEMBL569399 | 0.76 | TTK (0.39) | MAPT | |
| SCHEMBL569785 | 0.76 | HDAC8 (0.42) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |