Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 11/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008880 | 1.00 | NOD1 (0.43) | NOD1SLC6A5ACE2GNPATFPR2 | |
| SCHEMBL4009812 | 0.90 | NOD1 (0.48) | NOD1SLC6A5ACE2GNPATHDAC2 | |
| SCHEMBL5698138 | 0.90 | NOD1 (0.48) | NOD1SLC6A5ACE2GNPATHDAC2 | |
| SCHEMBL4007723 | 0.88 | NOD1 (0.41) | NOD1SLC6A5GNPATMMESLC15A2 | |
| SCHEMBL7175771 | 0.88 | NOD1 (0.49) | NOD1SLC6A5GNPATFPR2MME | |
| SCHEMBL7175773 | 0.88 | NOD1 (0.49) | NOD1SLC6A5GNPATFPR2MME | |
| SCHEMBL19586695 | 0.82 | FOLH1 (0.42) | NOD1SLC6A5GNPATMMESLC15A2 | |
| SCHEMBL19586694 | 0.82 | FOLH1 (0.42) | NOD1SLC6A5GNPATMMESLC15A2 | |
| SCHEMBL7176522 | 0.81 | NOD1 (0.58) | NOD1SLC6A5GNPATHDAC2 | |
| SCHEMBL7176520 | 0.81 | NOD1 (0.58) | NOD1SLC6A5GNPATHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670750-A1 | PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA- PROTEIN | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030703-A1 | PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE α2δ- PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2005-04-07 | — | — | WO | claimed |