Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5698223

N.O=S(=O)(O)CCN1CCN(CCO)CC1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
KMT2A Q03164 4/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
HSD11B1 P28845 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GAA P10253 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL7087618 0.98 ALDH1A1 (0.42) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL2417 0.98 ALDH1A1 (0.45) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL9790 0.98 ALDH1A1 (0.45) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL2229127 0.98 ALDH1A1 (0.45) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL21752977 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL21752879 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL3653844 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL21752846 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL21752841 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT
Sulfuric Acid SCHEMBL6545396 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060228766-A1 Assay for detection of transferase enzyme activity in drug screening ASTRAZENECA AB (SE) 2006-10-12 US disclosed
EP-1292701-B1 ASSAY FOR DETECTION OF TRANSFERASE ENZYME ACTIVITY IN DRUG SCREENING ASTRAZENECA AB (SE) 2006-08-09 EP disclosed
US-20060172361-A1 Assay for detection of translocase enzyme activity in drug screening ASTRAZENECA AB (SE) 2006-08-03 US disclosed
US-20030143635-A1 Assay for detection of transferase enzyme activity in drug screening ASTRAZENECA AB (SE) 2003-07-31 US disclosed
US-20030108969-A1 Assay for detection of translocase enzyme activity in drug screening ASTRAZENECA AB (SE) 2003-06-12 US disclosed
EP-1292702-A1 ASSAY FOR DETECTION OF TRANSLOCASE ENZYME ACTIVITY IN DRUG SCREENING AstraZeneca AB (SE) 2003-03-19 EP disclosed
EP-1292701-A1 ASSAY FOR DETECTION OF TRANSFERASE ENZYME ACTIVITY IN DRUG SCREENING AstraZeneca AB (SE) 2003-03-19 EP disclosed
WO-2001094623-A1 ASSAY FOR DETECTION OF TRANSLOCASE ENZYME ACTIVITY IN DRUG SCREENING ASTRAZENECA AB (SE) 2001-12-13 WO disclosed
WO-2001094622-A1 ASSAY FOR DETECTION OF TRANSFERASE ENZYME ACTIVITY IN DRUG SCREENING ASTRAZENECA AB (SE) 2001-12-13 WO disclosed
US-5358722-A Ferritin analogs MONSANTO COMPANY (US) 1994-10-25 US disclosed
US-5304382-A Combining apoferritin with non-ferrihydrite-forming solute, allowing permeation, disassembling, recovering core as spheres MONSANTO COMPANY (US) 1994-04-19 US disclosed
EP-0487615-B1 FERRITIN ANALOGS MONSANTO CO (US) 1994-01-05 EP disclosed
EP-0487615-A1 FERRITIN ANALOGS. MONSANTO CO (US) 1992-06-03 EP disclosed
WO-1991002704-A1 FERRITIN ANALOGS MONSANTO COMPANY (US) 1991-03-07 WO disclosed