SCHEMBL5698236

SCHEMBL5698236

C1=C2CCCCCCCCCCC2=CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091012 1.00 ALDH1A1 (0.32) ALDH1A1TRIM24TRIM33
SCHEMBL7772745 1.00 ALDH1A1 (0.32) ALDH1A1TRIM24TRIM33
SCHEMBL5698299 1.00 ALDH1A1 (0.32) ALDH1A1TRIM24TRIM33
SCHEMBL401311 0.96
SCHEMBL8091227 0.89
SCHEMBL3502363 0.76 TYMP (0.41) ALDH1A1
SCHEMBL3233355 0.76 TYMP (0.41) ALDH1A1
SCHEMBL2105114 0.76 TYMP (0.41) ALDH1A1
SCHEMBL11201526 0.76 TYMP (0.41) ALDH1A1
SCHEMBL21057468 0.76 TYMP (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900517-A Cyclopentadienyl derivatives and process for their preparation ENICHEM S.P.A. (IT) 1999-05-04 US claimed
EP-0760355-A1 Cyclopentadienyl derivatives and process for their preparation ENICHEM S.p.A. (IT) 1997-03-05 EP claimed
EP-1250342-B1 BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS POLIMERI EUROPA SPA (IT) 2006-06-28 EP disclosed
EP-0780395-B1 Catalysts for the polymerization of alpha-olefins ENICHEM SPA (IT) 2001-08-29 EP disclosed
CN-1066736-C Bridged cyclopentadienyl derivatives and process for their preparation ENICHEM SPA (IT) 2001-06-06 CN disclosed
US-6139484-A A CHEMICAL INTERMEDIATE FOR THE HYDROGENATION PROCESS OF THE COMPLEX WITH ZIRCONIUM TO FORM A POLYMERIZATION CATALYST ENICHEM S.P.A. (IT) 2000-10-31 US disclosed
EP-0773205-B1 Bridged cyclopentadienyl derivatives and process for their preparation ENICHEM SPA (IT) 1999-12-22 EP disclosed
EP-0760355-B1 Process for the preparation of cyclopentadienyl derivatives ENICHEM SPA (IT) 1999-10-27 EP disclosed
US-5917072-A CYCLOPENTADIENYL ZIRCONIUM COMPOUNDS ENICHEM S.P.A. (IT) 1999-06-29 US disclosed
US-5900517-A Cyclopentadienyl derivatives and process for their preparation ENICHEM S.P.A. (IT) 1999-05-04 US disclosed
CN-1158861-A Catalysts for polymerization of alpha-olefins ENICHEM SPA (IT) 1997-09-10 CN disclosed
EP-0780395-A1 Catalysts for the polymerization of alpha-olefins ENICHEM S.p.A. (IT) 1997-06-25 EP disclosed
EP-0773205-A1 Bridged cyclopentadienyl derivatives and process for their preparation ENICHEM S.p.A. (IT) 1997-05-14 EP disclosed
EP-0760355-A1 Cyclopentadienyl derivatives and process for their preparation ENICHEM S.p.A. (IT) 1997-03-05 EP disclosed