Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698294 | 0.85 | KDM4E (0.52) | KDM4EHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL553715 | 0.77 | KDM4E (0.57) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31602276 | 0.77 | KDM4E (0.57) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL553714 | 0.77 | KDM4E (0.57) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5693574 | 0.75 | GRIN2D (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5918256 | 0.75 | GRIN2D (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28201552 | 0.75 | GRIN2D (0.59) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6234937 | 0.75 | GRIN2D (0.55) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL563351 | 0.74 | KDM4E (0.51) | KDM4EHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL8865007 | 0.74 | KDM4E (0.55) | KDM4EHDAC8HDAC6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933682-B1 | Radiation-sensitive compositions with binders of polymers comprising N-substituted maleimide units | AGFA GEVAERT (BE) | 2006-08-09 | — | — | EP | disclosed |
| US-6190825-B1 | N-(P-AMINOSULFONYL)PHENYL-SUBSTITUTED | AGFA-GEVAERT N.V. (BE) | 2001-02-20 | — | — | US | disclosed |
| EP-0933682-A2 | Polymers comprising N-substituted maleimide units and their use in radiation-sensitive compositions | Agfa-Gevaert AG (DE) | 1999-08-04 | — | — | EP | disclosed |