SCHEMBL5698270

SCHEMBL5698270

C=CCOCC1(CC=C)COC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
PDE9A O76083 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198289 0.90 PDE9A (0.36) PDE9A
SCHEMBL633580 0.82 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9903979 0.79 PDE9A (0.41) PDE9A
SCHEMBL2106334 0.78 PDE9A (0.32) PDE9A
SCHEMBL5710810 0.77 ALDH1A1 (0.50) ALDH1A1PDE9A
SCHEMBL11037080 0.76 PDE9A (0.34) PDE9A
SCHEMBL761610 0.73 EPHX1 (0.38) ALDH1A1
SCHEMBL17985081 0.70
SCHEMBL1533016 0.70
SCHEMBL2493825 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270563-B1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF DAIKIN IND LTD (JP) 2006-06-07 EP claimed
US-6673948-B2 FLUORINATION CORRESPONDING OXETANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2004-01-06 US claimed
US-20030065199-A1 Fluorinated oxetane derivatives and production process thereof DAIKIN INDUSTRIES, LTD. (JP) 2003-04-03 US claimed
EP-1270563-A1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF Daikin Industries, Ltd. (JP) 2003-01-02 EP claimed
EP-1270563-B1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF DAIKIN IND LTD (JP) 2006-06-07 EP disclosed
EP-1270563-B1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF DAIKIN IND LTD (JP) 2006-06-07 EP disclosed
US-6673948-B2 FLUORINATION CORRESPONDING OXETANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2004-01-06 US disclosed
US-6673948-B2 FLUORINATION CORRESPONDING OXETANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2004-01-06 US disclosed
EP-1270563-A4 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF DAIKIN IND LTD (JP) 2003-06-18 EP disclosed
US-20030065199-A1 Fluorinated oxetane derivatives and production process thereof DAIKIN INDUSTRIES, LTD. (JP) 2003-04-03 US disclosed
US-20030065199-A1 Fluorinated oxetane derivatives and production process thereof DAIKIN INDUSTRIES, LTD. (JP) 2003-04-03 US disclosed
EP-1270563-A1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF Daikin Industries, Ltd. (JP) 2003-01-02 EP disclosed
EP-1270563-A1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF Daikin Industries, Ltd. (JP) 2003-01-02 EP disclosed
WO-2001074799-A1 FLUORINATED OXETANE DERIVATIVES AND PRODUCTION PROCESS THEREOF DAIKIN INDUSTRIES, LTD. (JP) 2001-10-11 WO disclosed
JP-2001278874-A FLUORINATED OXETANE DERIVATIVE AND METHOD FOR PRODUCING THE SAME DAIKIN IND LTD 2001-10-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065199-A1 Fluorinated oxetane derivatives and production process thereof FLI1, AFF1, CYP2F1 ALDH1A1 273/4885PDE9A 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.