Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662044 | 0.72 | TSHR (0.50) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL18878050 | 0.72 | TSHR (0.50) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL11630028 | 0.71 | TSHR (0.49) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL19121791 | 0.70 | TSHR (0.51) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL16752384 | 0.70 | TSHR (0.65) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL30689774 | 0.70 | TSHR (0.54) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| Diethyl Phthalate SCHEMBL29404255 | 0.69 | TSHR (1.00) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| Diethyl Phthalate SCHEMBL22296 | 0.69 | TSHR (1.00) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| Diethyl Phthalate SCHEMBL5306972 | 0.69 | TSHR (1.00) | TSHRALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL5386421 | 0.69 | TSHR (0.62) | TSHRALDH1A1HSD17B10MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250342-B1 | BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS | POLIMERI EUROPA SPA (IT) | 2006-06-28 | — | — | EP | disclosed |
| US-6984703-B1 | Bridged metallocene compounds as olefin-polymerization catalysts | POLIMERI EUROPA S.P.A. (IT) | 2006-01-10 | — | — | US | disclosed |
| EP-1250342-A1 | BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS | Polimeri Europa S.p.A. (IT) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001040238-A1 | BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS | POLIMERI EUROPA S.P.A. (IT) | 2001-06-07 | — | — | WO | disclosed |