Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111359 | 0.88 | CES1 (0.48) | CES1CES2LMNAELANETSHR | |
| SCHEMBL16111356 | 0.88 | CES1 (0.48) | CES1CES2LMNAELANETSHR | |
| SCHEMBL19127776 | 0.83 | ESR1 (0.50) | CES2LMNATSHRMAPTCYP3A4 | |
| Benzoic Acid SCHEMBL11306418 | 0.83 | TSHR (0.61) | CES1CES2LMNATSHRMAPT | |
| SCHEMBL10615120 | 0.83 | CES1 (0.52) | CES1CES2LMNATSHRMAPT | |
| SCHEMBL20564213 | 0.81 | CES1 (0.50) | CES1CES2LMNAELANETSHR | |
| SCHEMBL5491615 | 0.81 | CES1 (0.50) | CES1CES2LMNAELANETSHR | |
| SCHEMBL20564211 | 0.81 | CES1 (0.50) | CES1CES2LMNAELANETSHR | |
| SCHEMBL4613506 | 0.81 | CES2 (0.50) | CES1CES2MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8408970 | 0.81 | CES1 (0.50) | CES1CES2LMNAELANETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144542-B1 | POLYMER CEMENT ADDITIVE, CEMENT COMPOSITION AND PROCESS THEREWITH | CONOCOPHILLIPS CO (US) | 2006-07-19 | — | — | EP | claimed |