Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | MMP8 | P22894 | 3/20 | 0.57 |
| ▸ | MMP13 | P45452 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | USP1 | O94782 | 1/20 | 0.47 |
| ▸ | USP19 | O94966 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788689 | 0.94 | KMT2A (0.62) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL9149329 | 0.87 | KMT2A (0.56) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL11752008 | 0.85 | KMT2A (0.72) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL11749411 | 0.85 | KMT2A (0.72) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL4258701 | 0.84 | KMT2A (0.63) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL5698593 | 0.84 | KMT2A (1.00) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL15428326 | 0.84 | MMP2 (0.56) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL11752848 | 0.84 | KMT2A (0.71) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL11753888 | 0.84 | KMT2A (0.71) | KMT2AMMP2MMP9MMP8MMP13 | |
| SCHEMBL29421027 | 0.83 | KMT2A (0.55) | KMT2AMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734519-B1 | ANTI-BIOFILM COMPOUNDS | UNIV LOUISVILLE RES FOUND (US) | 2016-05-04 | — | — | EP | disclosed |
| US-9167820-B2 | Anti-biofilm compounds | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-9167820-B2 | Anti-biofilm compounds | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INC. (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2013016206-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | MSR1, NPR1, FPR1 | KMT2A 3907/4885MMP2 928/4885MMP9 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.