Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698665 | 0.86 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7216760 | 0.80 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL2466118 | 0.78 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL5309102 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5312028 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5311654 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5311840 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL28249029 | 0.75 | CHRNA7 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5311718 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5314089 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682143-A2 | COMBINATIONS COMPRISING AN HSP90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | Pharmacia Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044194-A2 | TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR | PHARMACIA CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005041879-A2 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |