Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594789 | 1.00 | PTGS2 (0.90) | PTGS2PTGS1 | |
| SCHEMBL3243606 | 1.00 | PTGS2 (0.90) | PTGS2PTGS1 | |
| SCHEMBL5594726 | 0.95 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213892 | 0.95 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594244 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL1930674 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL5594163 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL5594309 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL3245005 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL5594771 | 0.94 | PTGS2 (0.80) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682143-A2 | COMBINATIONS COMPRISING AN HSP90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | Pharmacia Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005041879-A2 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |