Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431164 | 0.95 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5422115 | 0.93 | MAPT (0.74) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5426307 | 0.82 | MAPT (0.74) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL17148029 | 0.82 | MEN1 (0.78) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| P-Anisic Acid SCHEMBL11874860 | 0.80 | CA1 (0.80) | ALDH1A1MAPTHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL28584650 | 0.80 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL4295568 | 0.79 | HIF1A (0.73) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17148036 | 0.78 | MAPT (0.76) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5660811 | 0.78 | GAA (0.60) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL9995867 | 0.77 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687256-A1 | NOVEL PHENOXYACETAMIDE DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF DIPHENYLAMINES | MERCK PATENT GmbH (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051892-A1 | NOVEL PHENOXYACETAMIDE DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF DIPHENYLAMINES | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |