SCHEMBL5698803

SCHEMBL5698803

C#COCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
CA9 Q16790 7/20 0.38
LPAR3 Q9UBY5 6/20 0.38
LPAR2 Q9HBW0 5/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
LPAR1 Q92633 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27950794 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL3665928 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL25825231 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL3663370 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL5698804 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL19520178 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL8778616 1.00 THRB (0.42) THRBTSHRMEN1HTTKMT2A
SCHEMBL7134703 1.00
SCHEMBL8218669 0.97
SCHEMBL387903 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2999737-B1 POLYMER CONTAINING HYDROXYSILANE AND SILANE GROUPS SIKA TECH AG (CH) 2017-03-15 EP claimed
EP-1266913-B1 Flow-and-leveling agents for powder coatings KUSUMOTO CHEMICALS (JP) 2006-08-02 EP claimed
EP-1266914-B1 Flow-and-levelling agents for waterborne coatings KUSUMOTO CHEMICALS (JP) 2006-08-02 EP claimed
EP-1021403-B1 2,3-DIOXABICYCLO 3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM YEDA RES & DEV (IL) 2005-04-20 EP claimed
EP-0210928-B1 EXTRACTING AGENTS AND PROPANE DIAMIDES, THEIR USE TO RECOVER ACTINIDES AND/OR LANTHANIDES AND PROCESS FOR THEIR PREPARATION COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-03-14 EP claimed
EP-0210928-A1 Extracting agents and propane diamides, their use to recover actinides and/or lanthanides and process for their preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1987-02-04 EP claimed
US-10711075-B2 Method of preparing rubber composition including syndiotactic 1,2-polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-07-14 US disclosed
US-20190023815-A1 METHOD OF PREPARING RUBBER COMPOSITION INCLUDING SYNDIOTACTIC 1,2-POLYBUTADIENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2019-01-24 US disclosed
EP-0512901-B1 Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1999-06-23 EP disclosed
EP-0591040-B1 Quaternary basic amides as tachykinines antagonists SANOFI SA (FR) 1999-02-03 EP disclosed
EP-0474561-B1 Arylalkylamines, process for their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1998-12-09 EP disclosed
EP-0515240-B1 N-(aminoalkyl)piperidine compounds and their enantiomers as neurokinines receptors antagonists, processes for their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1997-09-24 EP disclosed
EP-0591040-A1 Quaternary basic amides as tachykinines antagonists SANOFI (FR) 1994-04-06 EP disclosed
EP-0375560-B1 ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ELF SANOFI (FR) 1993-05-12 EP disclosed
EP-0515240-A1 N-alkylidene piperidine compounds and their enatiomers, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1992-11-25 EP disclosed
EP-0512902-A1 Dialkyleneperidino compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1992-11-11 EP disclosed
EP-0512901-A1 Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1992-11-11 EP disclosed
EP-0474561-A1 Arylalkylamines, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1992-03-11 EP disclosed
EP-0428434-A2 Compounds of aromatic amines and their enantiomers, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1991-05-22 EP disclosed
EP-0375560-A1 Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same ELF SANOFI (FR) 1990-06-27 EP disclosed