Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 2/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.57 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 6/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030275 | 1.00 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL7034680 | 0.89 | HINT1 (0.50) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL5549083 | 0.87 | HINT1 (0.65) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL1274196 | 0.87 | HINT1 (0.65) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL1164486 | 0.86 | HINT1 (0.64) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL14957138 | 0.86 | HINT1 (0.64) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL599196 | 0.86 | HINT1 (0.68) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL18520136 | 0.85 | HINT1 (0.69) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL2275000 | 0.84 | HINT1 (0.66) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL3970953 | 0.84 | HINT1 (0.73) | HINT1NT5EGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018007-B1 | ADDRESSABLE MODULAR RECOGNITION SYSTEM, PRODUCTION MODE AND USE | NANOGEN RECOGNOMICS GMBH (DE) | 2006-07-26 | — | — | EP | claimed |
| EP-1018007-B1 | ADDRESSABLE MODULAR RECOGNITION SYSTEM, PRODUCTION MODE AND USE | NANOGEN RECOGNOMICS GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| EP-1018007-A1 | ADDRESSABLE MODULAR RECOGNITION SYSTEM, PRODUCTION MODE AND USE | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015893-A1 | ADDRESSABLE MODULAR RECOGNITION SYSTEM, PRODUCTION MODE AND USE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |