SCHEMBL5698934

SCHEMBL5698934

C=CC(=O)OCCCC[SiH](OCCCC)OCCCC

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.69
HPGD P15428 1/20 0.69
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 1/20 0.55
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 3/20 0.44
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.40
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NAAA Q02083 1/20 0.36
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140103 0.95 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1285195 0.92 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL16286805 0.91 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL5698950 0.90 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL110716 0.87 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL107694 0.87 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL16286693 0.86 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL16286758 0.86 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL7470091 0.83 TSHR (0.92) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL15037 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036834-B1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL NIPPON CATALYTIC CHEM IND (JP) 2006-06-14 EP disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
EP-1036834-A1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL Nippon Shokubai Co., Ltd. (JP) 2000-09-20 EP disclosed
US-6037394-A ACRYLIC RESIN, BENZOTRIAZOLE, SOLVENT, AND ALKOXYSILANE REACTION PRODUCT WITH SILYLATION AGENT; PROTECTIVE COATINGS, WEAR RESISTANCE, WEATHERPROOFING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-03-14 US disclosed
EP-0934987-A1 Primer composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
US-5025049-A Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-18 US disclosed