SCHEMBL110716

SCHEMBL110716

C=CC(=O)OCCCC[SiH](OCC)OCC

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.58
ALDH1A1 P00352 4/20 0.58
CYP3A4 P08684 2/20 0.58
HPGD P15428 1/20 0.58
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 4/20 0.38
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16286693 0.98 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286758 0.98 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL81412 0.95 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1285195 0.89 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL238023 0.88 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20492166 0.88 TSHR (0.45) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286805 0.87 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5698934 0.87 TSHR (0.69) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28044457 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21081906 0.85 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
US-11975125-B2 Medical devices MICROVENTION, INC. (US) 2024-05-07 US claimed
EP-3860669-B1 MEDICAL DEVICES MICROVENTION INC (US) 2024-04-03 EP claimed
US-20230330309-A1 MEDICAL DEVICES MICROVENTION, INC. 2023-10-19 US claimed
US-11725136-B2 Process for manufacturing light absorbing polymer matrix ESSILOR INTERNATIONAL (FR) 2023-08-15 US claimed
EP-4223409-A1 LITHIUM ION ADSORBENTS Conductive Energy Inc. (CA) 2023-08-09 EP claimed
US-20230241581-A1 LITHIUM ION ADSORBENTS CONDUCTIVE ENERGY INC. (CA) 2023-08-03 US claimed
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
US-11590267-B2 Medical devices MICROVENTION, INC. (US) 2023-02-28 US claimed
EP-3505562-B1 PROCESS FOR MANUFACTURING LIGHT ABSORBING POLYMER MATRIX ESSILOR INT (FR) 2022-09-14 EP claimed
US-6475347-B1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION 2002-11-05 US claimed
US-20020061407-A1 Abrasion resistant coating composition and coated articles PPG INDUSTRIES OHIO, INC. 2002-05-23 US claimed
US-6334935-B1 DISTILLING REACTION SOLUTION CONTAINING (METH)ACRY LOXY-BEARING ALKOXYSILANE IN THIN-LAYER DISTILLATION DEVICE AT SPECIFIED TEMPERATURE AND VACUUM, WHEREIN MIST SEPARATOR IS CONNECTED TO DISTILLATION DEVICE FOR SEPARATING OFF MIST FROM S OLUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-01 US claimed
US-6051097-A WATER-SOLUBLE CONDENSATION POLYMER OBTAINED BY SUBJECTING A SPECIFIC COPOLYMER HAVING AN ALKOXYL GROUP AND A SPECIFIC ALKOXYSILANE TO HYDROLYSIS-CONDENSATION; BOND NON-SULFUR-CURABLE ELASTOMER MATERIALS TO VARIOUS ADHERENDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-04-18 US claimed
EP-0857771-A2 Aqueous adhesive composition, and bonding process and bonded article making use of the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-08-12 EP claimed
EP-0818496-A2 Method for making aqueous emulsions of functionalized organic polymers DOW CORNING CORPORATION (US) 1998-01-14 EP claimed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5449716-A Curable composition of silane and polysiloxanes with catalyst DOW CORNING CORPORATION (US) 1995-09-12 US claimed
US-4543403-A .MOISTURE CURABLE SILANE ENDCAPPED ACRYLIC POLYMER, TELECHELIC KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-09-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629657-B2 Lithium ion adsorbents ILK, SDC1, LAMTOR3 TSHR 3614/4885ALDH1A1 2379/4885CYP3A4 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.