Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 3/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.40 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668161 | 0.87 | PDE2A (0.56) | CES2CES1PDE2AACP3AKR1C3 | |
| SCHEMBL29400701 | 0.86 | CES2 (0.55) | CES2CES1PDE2AACP3ORAI1 | |
| Ammonia Solution, Strong SCHEMBL9789504 | 0.85 | PDE2A (0.55) | CES2CES1PDE2AACP3AKR1C3 | |
| SCHEMBL24298277 | 0.83 | KDM4E (0.55) | CES2CES1PDE2A | |
| SCHEMBL27765175 | 0.83 | KDM4E (0.55) | CES2CES1PDE2A | |
| SCHEMBL835747 | 0.83 | KDM4E (0.55) | CES2CES1PDE2A | |
| SCHEMBL24298279 | 0.83 | KDM4E (0.55) | CES2CES1PDE2A | |
| SCHEMBL991083 | 0.82 | PTPN5 (0.55) | CES2CES1PDE2AACP3AKR1C3 | |
| SCHEMBL5451341 | 0.82 | PTPN5 (0.55) | CES2CES1PDE2AACP3AKR1C3 | |
| SCHEMBL342466 | 0.82 | PTPN5 (0.55) | CES2CES1PDE2AACP3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673463-A1 | METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS | Rhodia Chimie (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005038036-A1 | METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS | RHODIA CHIMIE (FR) | 2005-04-28 | — | — | WO | disclosed |