Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566743 | 0.86 | TSHR (0.36) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5699110 | 0.85 | TSHR (0.37) | THRBTSHRHPGDALDH1A1 | |
| SCHEMBL5699056 | 0.85 | TSHR (0.39) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5699158 | 0.83 | TSHR (0.35) | THRBTSHRHPGD | |
| SCHEMBL5698992 | 0.82 | TSHR (0.37) | THRBTSHRHPGD | |
| SCHEMBL5699084 | 0.80 | TSHR (0.35) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5699055 | 0.78 | TSHR (0.35) | THRBTSHRALDH1A1 | |
| SCHEMBL7568455 | 0.75 | TSHR (0.39) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5699082 | 0.73 | TSHR (0.42) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL7568811 | 0.72 | TSHR (0.37) | THRBTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238980-B1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SHINETSU CHEMICAL CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-6498264-B2 | REACTING A CHLOROSILANE COMPOUND WITH ACRYLIC OR METHACRYLIC ACID IN THE PRESENCE OF A BASIC COMPOUND; PROTECTIVE HYDROLYSABLE COATINGS FOR SHIP BOTTOMS; NONTOXIC; POLLUTION CONTROL; KINETICS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| EP-1238980-A1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-09-11 | — | — | EP | disclosed |