Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699158 | 0.94 | TSHR (0.35) | TSHRTHRBHPGD | |
| SCHEMBL5699084 | 0.88 | TSHR (0.35) | TSHRTHRBHPGDALDH1A1 | |
| SCHEMBL5699056 | 0.87 | TSHR (0.39) | TSHRTHRBHPGDALDH1A1 | |
| SCHEMBL7568455 | 0.87 | TSHR (0.39) | TSHRTHRBHPGDALDH1A1 | |
| SCHEMBL5699003 | 0.85 | THRB (0.35) | TSHRTHRBHPGDALDH1A1 | |
| SCHEMBL5699020 | 0.84 | TSHR (0.37) | TSHRTHRBHPGD | |
| SCHEMBL7568811 | 0.84 | TSHR (0.37) | TSHRTHRBHPGD | |
| SCHEMBL5699096 | 0.81 | TSHR (0.35) | TSHRHPGD | |
| SCHEMBL5699026 | 0.79 | TSHR (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL5838286 | 0.75 | TSHR (0.44) | TSHRTHRBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238980-B1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SHINETSU CHEMICAL CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-6498264-B2 | REACTING A CHLOROSILANE COMPOUND WITH ACRYLIC OR METHACRYLIC ACID IN THE PRESENCE OF A BASIC COMPOUND; PROTECTIVE HYDROLYSABLE COATINGS FOR SHIP BOTTOMS; NONTOXIC; POLLUTION CONTROL; KINETICS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| US-20020128503-A1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1238980-A1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128503-A1 | Silyl (meth)acrylates having bulky substituent group and preparation thereof | SMS, MASTL, ACR | TSHR 4007/4885THRB 1319/4885HPGD 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.