SCHEMBL5699016

SCHEMBL5699016

C=C(C)COC[Si](C)(OCCCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.32
CES2 O00748 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757137 0.95
SCHEMBL237864 0.89
SCHEMBL11762971 0.84 CES2 (0.34) TSHRCES2ALDH1A1
SCHEMBL5698944 0.84 TSHR (0.33) TSHRCES2ALDH1A1
SCHEMBL2904711 0.83 CES2 (0.37) TSHRCES2
SCHEMBL666440 0.83
SCHEMBL143880 0.81
SCHEMBL853988 0.80
SCHEMBL11745741 0.76 CES2 (0.40) TSHRCES2ALDH1A1
SCHEMBL6408574 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036834-B1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL NIPPON CATALYTIC CHEM IND (JP) 2006-06-14 EP disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
EP-1036834-A1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL Nippon Shokubai Co., Ltd. (JP) 2000-09-20 EP disclosed
US-6037394-A ACRYLIC RESIN, BENZOTRIAZOLE, SOLVENT, AND ALKOXYSILANE REACTION PRODUCT WITH SILYLATION AGENT; PROTECTIVE COATINGS, WEAR RESISTANCE, WEATHERPROOFING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-03-14 US disclosed
EP-0934987-A1 Primer composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed