Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27370690 | 0.82 | CSNK1E (0.53) | SPHK1LMNAKDM4EALDH1A1CSNK1E | |
| SCHEMBL6911548 | 0.82 | ESR1 (0.44) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL27555697 | 0.82 | HIF1A (0.52) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL12087597 | 0.82 | HIF1A (0.52) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL10457370 | 0.82 | HIF1A (0.52) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL27981045 | 0.82 | HIF1A (0.52) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL4860981 | 0.82 | HIF1A (0.52) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL25172266 | 0.80 | ESR1 (0.50) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL6745552 | 0.80 | ESR1 (0.50) | NR5A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL4410688 | 0.80 | ESR1 (0.50) | NR5A1ESR1ADORA3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516866-B1 | NATURAL COMPOUNDS AND DERIVATIVES THEREOF FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, HEPATIC AND RENAL DISEASES AND FOR COSMETIC APPLICATIONS | PULEVA BIOTECH SA (ES) | 2006-07-12 | — | — | EP | claimed |