Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 13/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arimoclomol SCHEMBL2324741 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL1896428 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL12254223 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL25257807 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL12254225 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL25258754 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL196123 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL5699241 | 0.88 | HSF1 (0.54) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL7052423 | 0.87 | HSF1 (0.53) | HSF1ABCB1 | |
| Arimoclomol SCHEMBL5699253 | 0.87 | HSF1 (0.53) | HSF1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126002-B2 | Pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds | CYTRX CORPORATION (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1274685-B1 | A PYRIDINE-N-OXIDE DERIVATIVE, AND PROCESS FOR ITS TRANSFORMATION INTO PHARMACEUTICALLY EFFECTIVE COMPOUNDS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2006-07-12 | — | — | EP | disclosed |
| US-20040006232-A1 | Pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds | KEMPHARM, INC. | 2004-01-08 | — | — | US | disclosed |
| EP-1274685-A1 | A PYRIDINE-1-OXIDE DERIVATIVE, AND PROCESS FOR ITS TRANSFORMATION INTO PHARMACEUTICALLY EFFECTIVE COMPOUNDS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001079174-A1 | A PYRIDINE-1-OXIDE DERIVATIVE, AND PROCESS FOR ITS TRANSFORMATION INTO PHARMACEUTICALLY EFFECTIVE COMPOUNDS | BIOREX Kutató és Fejlesztő Rt. (HU) | 2001-10-25 | — | — | WO | disclosed |