Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699498 | 0.75 | FAAH (0.36) | EPHX2FAAHTRPV1CES1 | |
| SCHEMBL21217064 | 0.70 | MAPT (0.48) | MAPT | |
| SCHEMBL21210733 | 0.70 | MAPT (0.48) | MAPT | |
| SCHEMBL22654037 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL24218814 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL22654062 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL25362976 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL23040321 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL23291808 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 | |
| SCHEMBL23040322 | 0.67 | FAAH (0.74) | MAPTFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846781-B2 | Oxadiazole additives for lubricants | CROMPTON CORPORATION (US) | 2005-01-25 | — | — | US | claimed |
| EP-1392805-B1 | OXADIAZOLE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2006-08-02 | — | — | EP | disclosed |