Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224510 | 1.00 | MAPT (0.47) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL6558491 | 1.00 | MAPT (0.47) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL971931 | 0.98 | MAPT (0.44) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL11682358 | 0.92 | MAPT (0.41) | MAPTALDH1A1TSHRMEN1LMNA | |
| SCHEMBL5699522 | 0.90 | EPHX2 (0.40) | MAPT | |
| SCHEMBL5699528 | 0.90 | EPHX2 (0.40) | MAPT | |
| SCHEMBL1063939 | 0.83 | MAPT (0.52) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL14489684 | 0.78 | MAPT (0.48) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL21217064 | 0.78 | MAPT (0.48) | MAPTALDH1A1KCNH2TSHRMEN1 | |
| SCHEMBL21210733 | 0.78 | MAPT (0.48) | MAPTALDH1A1KCNH2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392805-B1 | OXADIAZOLE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2006-08-02 | — | — | EP | disclosed |