Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 12/20 | 0.60 |
| ▸ | RARB | P10826 | 9/20 | 0.60 |
| ▸ | RARA | P10276 | 9/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699564 | 0.86 | RARG (0.49) | RARGRARBRARARXRAPPARG | |
| SCHEMBL956426 | 0.86 | RARG (0.76) | RARGRARBRARARXRA | |
| SCHEMBL5699630 | 0.85 | RARG (0.48) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699604 | 0.85 | RARG (0.47) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699620 | 0.83 | RARG (0.47) | RARGRARBRARARXRAALDH1A1 | |
| SCHEMBL955718 | 0.83 | RARG (0.81) | RARGRARBRARARXRA | |
| SCHEMBL5699634 | 0.81 | RARG (0.52) | RARGRARBRARARXRA | |
| SCHEMBL956961 | 0.81 | RARG (0.77) | RARGRARBRARARXRAALDH1A1 | |
| SCHEMBL955111 | 0.80 | RARG (0.75) | RARGRARBRARARXRAALDH1A1 | |
| SCHEMBL955261 | 0.78 | RARG (0.94) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056516-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-23 | — | — | WO | disclosed |