Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.47 |
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | RARA | P10276 | 9/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699563 | 0.86 | RARG (0.54) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699630 | 0.86 | RARG (0.48) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699564 | 0.85 | RARG (0.49) | RARGRARBRARARXRAPPARG | |
| SCHEMBL955177 | 0.85 | RARG (0.61) | RARGRARBRARARXRA | |
| SCHEMBL5699588 | 0.85 | RARG (0.60) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699620 | 0.84 | RARG (0.47) | RARGRARBRARARXRA | |
| SCHEMBL955219 | 0.81 | RARG (0.63) | RARGRARBRARARXRA | |
| SCHEMBL5699634 | 0.81 | RARG (0.52) | RARGRARBRARARXRA | |
| SCHEMBL956949 | 0.78 | RARG (0.76) | RARGRARBRARARXRA | |
| SCHEMBL4654649 | 0.78 | RARG (0.62) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056516-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-23 | — | — | WO | disclosed |