Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700134 | 1.00 | CCR5 (0.76) | CCR5 | |
| SCHEMBL5699769 | 0.86 | CCR5 (1.00) | CCR5 | |
| SCHEMBL5699760 | 0.86 | CCR5 (1.00) | CCR5 | |
| SCHEMBL5699935 | 0.85 | CCR5 (0.78) | CCR5 | |
| SCHEMBL5699961 | 0.85 | CCR5 (1.00) | CCR5 | |
| SCHEMBL5700445 | 0.84 | CCR5 (0.77) | CCR5 | |
| SCHEMBL5699941 | 0.82 | CCR5 (0.82) | CCR5 | |
| SCHEMBL5699710 | 0.82 | CCR5 (0.88) | CCR5 | |
| SCHEMBL5699896 | 0.81 | CCR5 (1.00) | CCR5 | |
| SCHEMBL5700007 | 0.81 | CCR5 (0.80) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687268-A1 | BENZYLETHER AMINE COMPOUNDS USEFUL AS CCR-5 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005047249-A1 | BENZYLETHER AMINE COMPOUNDS USEFUL AS CCR-5 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-05-26 | — | — | WO | claimed |