Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700150 | 1.00 | SHBG (0.72) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| SCHEMBL5700149 | 0.91 | SHBG (0.76) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| SCHEMBL5700143 | 0.91 | SHBG (0.76) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| Bolasterone SCHEMBL10904938 | 0.84 | SHBG (1.00) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| SCHEMBL8340653 | 0.84 | SHBG (0.82) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| Bolasterone SCHEMBL145066 | 0.84 | SHBG (1.00) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| Bolasterone SCHEMBL11876760 | 0.84 | SHBG (1.00) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| SCHEMBL8340651 | 0.84 | SHBG (0.82) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| Calusterone SCHEMBL4509 | 0.84 | SHBG (1.00) | SHBGCYP19A1ALDH1A1ARNR3C1 | |
| Bolasterone SCHEMBL5656551 | 0.84 | SHBG (1.00) | SHBGCYP19A1ALDH1A1ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | claimed |
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | CYP17A1, CYP21A2, NR5A1 | SHBG 43/4885CYP19A1 6/4885ALDH1A1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.