SCHEMBL5700328

SCHEMBL5700328

C#Cc1ccnc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29562545 1.00
SCHEMBL448261 0.77
SCHEMBL30295272 0.77
SCHEMBL20448774 0.77
SCHEMBL1332757 0.76 HDAC8 (0.50)
SCHEMBL31646249 0.76 HDAC8 (0.50)
SCHEMBL4737755 0.73
SCHEMBL5700225 0.73
SCHEMBL16289493 0.73
SCHEMBL4038329 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134872-B Metal coordination heteroatom-containing organic microporous material and preparation and application thereof 东华大学 2021-06-11 CN claimed
CN-109134872-A A kind of coordination of metal is containing the organic poromerics of hetero atom and its preparation and application 东华大学 2019-01-04 CN claimed
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 US disclosed
WO-2025090658-A2 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-05-01 WO disclosed
CN-109134872-B Metal coordination heteroatom-containing organic microporous material and preparation and application thereof 东华大学 2021-06-11 CN disclosed
CN-109134872-B Metal coordination heteroatom-containing organic microporous material and preparation and application thereof 东华大学 2021-06-11 CN disclosed
EP-2704571-B1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME (US) 2020-04-22 EP disclosed
EP-2704571-B1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME (US) 2020-04-22 EP disclosed
EP-2934525-B1 THIAZOLE-SUBSTITUTED AMINOPYRIDINES AS SPLEEN TYROSINE KINASE INHIBITORS MERCK SHARP & DOHME (US) 2019-05-08 EP disclosed
CN-109134872-A A kind of coordination of metal is containing the organic poromerics of hetero atom and its preparation and application 东华大学 2019-01-04 CN disclosed
CN-109134872-A A kind of coordination of metal is containing the organic poromerics of hetero atom and its preparation and application 东华大学 2019-01-04 CN disclosed
CN-103619170-A Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors MERCK SHARP & DOHME 2014-03-05 CN disclosed
US-20130090309-A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME LLC 2013-04-11 US disclosed
US-20130090309-A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME LLC 2013-04-11 US disclosed
US-20130090309-A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME LLC 2013-04-11 US disclosed
WO-2012151137-A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-11-08 WO disclosed
EP-1270582-B1 TRIPHENYLPHOSPHINE DERIVATIVES, PALLADIUM OR NICKEL COMPLEXES THEREOF, AND PROCESS FOR PREPARING BIARYL DERIVATIVES MITSUBISHI RAYON CO (JP) 2006-08-30 EP disclosed
US-6693210-B2 USING PALLADIUM, NICKEL PHOSPHINE COMPLEX AS CATALYSTS MITSUBISHI RAYON CO., LTD. (JP) 2004-02-17 US disclosed
US-20030065208-A1 Using palladium, nickel phosphine complex as catalysts MITSUBISHI RAYON CO., LTD. (JP) 2003-04-03 US disclosed
EP-1270582-A1 TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2003-01-02 EP disclosed