Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | SHBG | P04278 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700374 | 1.00 | AR (0.41) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL5700105 | 0.91 | SHBG (0.39) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL5700101 | 0.91 | SHBG (0.39) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL4115264 | 0.85 | SHBG (0.55) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL13855720 | 0.85 | SHBG (0.55) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL28827028 | 0.85 | SHBG (0.55) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL4115261 | 0.85 | SHBG (0.55) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL28060038 | 0.85 | SHBG (0.55) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL13558383 | 0.81 | SERPINA6 (0.52) | ARSHBGMAPK1POLBLMNA | |
| SCHEMBL5909302 | 0.81 | SERPINA6 (0.52) | ARSHBGMAPK1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | claimed |
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| EP-1322660-A2 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | Schering AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002026759-A2 | 17α FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | CYP17A1, CYP21A2, NR5A1 | AR 60/4885SHBG 43/4885MAPK1 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.