⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948829 | 0.73 | — | — | |
| SCHEMBL16129944 | 0.69 | — | — | |
| SCHEMBL20111621 | 0.69 | — | — | |
| SCHEMBL9749302 | 0.69 | — | — | |
| SCHEMBL7635569 | 0.69 | — | — | |
| SCHEMBL8380249 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL7658475 | 0.65 | — | — | |
| SCHEMBL11527806 | 0.65 | KDM4E (0.48) | — | |
| SCHEMBL16051806 | 0.65 | — | — | |
| SCHEMBL7658483 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110373405-A | A kind of biological enzyme of graft polymers and preparation method thereof and fixing means | 西安理工大学 | 2019-10-25 | — | — | CN | claimed |
| CN-114206934-A | Encapsulated protein-6 bispecific antibodies | 加利福尼亚大学董事会 | 2022-03-18 | — | — | CN | disclosed |
| CN-114174340-A | Encapsulated protein-6 antibodies and drug conjugates | 加利福尼亚大学董事会 | 2022-03-11 | — | — | CN | disclosed |
| CN-113194985-A | EpCAM antibodies, activatable antibodies and immunoconjugates and uses thereof | 伊缪诺金公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20170152288-A1 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | NOVALIX DEUTSCHLAND GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| EP-3065780-A1 | ANTI-EFNA4 ANTIBODY-DRUG CONJUGATES | Pfizer Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9125847-B2 | A-β immunogenic peptide carrier conjugates and methods of producing same | JANSSEN SCIENCES IRELAND UC (IE) | 2015-09-08 | — | — | US | disclosed |
| US-9089510-B2 | A-β immunogenic peptide carrier conjugates and methods of producing same | JANSSEN SCIENCES IRELAND UC (IE) | 2015-07-28 | — | — | US | disclosed |
| EP-2298736-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2015065954-A1 | ANTI-EFNA4 ANTIBODY-DRUG CONJUGATES | PFIZER, INC. (US) | 2015-05-07 | — | — | WO | disclosed |
| EP-1752516-A1 | Dispersants | The Lubrizol Corporation (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20070027046-A1 | Novel Dispersants | THE LUBRIZOL CORPORATION (US) | 2007-02-01 | — | — | US | disclosed |
| US-6800728-B2 | CROSSLINKING AND IMMOBILIZING BIOMOLECULES, DRUGS AND SYNTHETIC POLYMERS WITH A THIOL OR AMINO REACTIVE GROUP AND HYDRAZINO OR OXYAMINO MOIETIES | SOLULINK BIOSCIENCES, INC. | 2004-10-05 | — | — | US | disclosed |
| US-20040110730-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | AUDAX PRIVATE DEBT LLC, AS AGENT | 2004-06-10 | — | — | US | disclosed |
| US-20030199466-A1 | For modulating an immune response | DYNAVAX TECHNOLOGIES CORPORATION | 2003-10-23 | — | — | US | disclosed |
| EP-1315699-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | Solulink, Incorporated (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030013857-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INCORPORATED | 2003-01-16 | — | — | US | disclosed |
| US-20020119095-A1 | Chemotherapeutic agents conjugated to p97 and their methods of use in treating neurological tumours | GABATHULER REINHARD (CA) | 2002-08-29 | — | — | US | disclosed |
| WO-2002013843-A2 | CHEMOTHERAPEUTIC AGENTS CONJUGATED TO P97 AND THEIR METHODS OF USE IN TREATING NEUROLOGICAL TUMOURS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001070685-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | SOLULINK, INCORPORATED (US) | 2001-09-27 | — | — | WO | disclosed |