SCHEMBL5700852

SCHEMBL5700852

O=[N+]([O-])c1cccc(/N=N/c2cc[c]cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.52
MEN1 O00255 6/20 0.52
KMT2A Q03164 6/20 0.52
MAPT P10636 5/20 0.52
MAPK1 P28482 1/20 0.52
TSHR P16473 3/20 0.52
LMNA P02545 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
CCNT1 O60563 1/20 0.51
CCNE2 O96020 1/20 0.51
CDK4 P11802 1/20 0.51
CCND1 P24385 1/20 0.51
CCNE1 P24864 1/20 0.51
CDK2 P24941 1/20 0.51
CDK9 P50750 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5700857 1.00 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL1405487 0.88 TSHR (0.67) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL1405486 0.88 TSHR (0.67) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL1405402 0.86 NPC1 (0.65) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL1405403 0.86 NPC1 (0.65) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL7309289 0.80 MEN1 (0.51) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL4291371 0.80 MEN1 (0.51) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL8142961 0.80 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL11456363 0.80 CCNT1 (0.58) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL11456364 0.80 CCNT1 (0.58) ALDH1A1MEN1KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063572-B1 Electrophotographic photosensitve member, and process cartridge and electrophotographic apparatus including the photosensitive member CANON KK (JP) 2006-08-23 EP claimed
US-6335132-B1 FOR FORMING IMAGES WITH LESS DEFECTS CANON KABUSHIKI KAISHA (JP) 2002-01-01 US claimed
EP-1063572-A1 Electrophotographic photosensitve member, and process cartridge and electrophotographic apparatus including the photosensitive member CANON KABUSHIKI KAISHA (JP) 2000-12-27 EP claimed